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Microneedling, which can also be known around the world by terms like dermarolling or collagen induction therapy, is a popular medical and cosmetic procedure that many people commonly turn to when seeking treatments to improve the overall appearance and health of their skin. It is a minimally invasive method when compared to others like laser resurfacing, in which fine, sterilized needles are pricked into the skin to create tiny puncture wounds or micro-injuries on its surface. The goal of this is to activate the body’s natural wound healing process, which increases collagen and elastin production, components that play vital roles in maintaining the youthful bounce of the skin, its smooth texture, and its plump firmness.
Exosomes essentially contribute a great deal to this sort of restorative procedure, and they are the minute, extracellular containers that exist within and around cells, generated by various cell types. Due to their mighty ability to host a diverse range of molecules like proteins, lipids, nucleic acids, and metabolites, exosomes are able to act as key mediators and communicators in the skin’s and body’s physiological processes. The benefits that stem from their involvement include encouraging tissue repair, modulating inflammation, and facilitating cellular regeneration, thereby boosting the optimal functioning of the skin. They accomplish this by transporting and delivering bioactive molecules to recipient cells, making them valuable vehicles for influencing cellular behavior and driving physiological responses.
When a microneedling treatment is performed on a patient, a handheld device with small needles, such as a derma roller or a microneedling pen, is then rolled or pressed onto the skin to inflict controlled damage onto the outermost layer (the epidermis), as well as the underlying dermis layers. The collagen that this induces within the skin will provide greater structure and support, while the increase in elastin fibers builds its resilience and elasticity that were lost as it aged. While collagen is already produced by the body naturally, the breakdown in cellular function and health over time disrupts this process because aging begins to slow everything down. So, treatments like microneedling strengthen the skin by giving it a bolster, returning it to its previously robust volume and levels of moisture retention.
Other outcomes that patients can achieve with microneedling are for the aesthetic purposes of lightening scars and reducing the number of visible wrinkles on their complexions. Scar tissue from acne or surgical wounds can be broken up and remodeled through the procedure, prompting the body’s collagen production to respond by healing up all the fresh puncture holes and promoting the formation of new skin cells. Wrinkles, enlarged pores, stretch marks, and fine lines can also be targeted with regular treatment, as the depth and severity are reduced with the amount of collagen that gets generated, and the results lead to a more rejuvenated appearance.
Inflammation is a common side effect that many patients will be exposed to post-procedure, especially if their skin type has been identified as particularly sensitive or reactive. There are anti-inflammatory properties in exosomes that can help stop the effects of microneedling by controlling the activity of immune cells and the production of cytokines. By doing so, these vesicles shorten the recovery period needed and minimize the redness, swelling, and discomfort that accompany the procedure’s outcomes. The micro-injuries that microneedling creates also allow for better absorption of topical skincare products, including professional microneedling serums by brands like Calecim, creams, and solutions that can contain exosomes. This way, all the active ingredients are delivered directly into the dermal layers, where their beneficial effects can more easily take root. As exosomes are so rich in growth factors, cytokines, and other bioactive molecules, they can penetrate rather deeply into the skin and its cells when applied after a microneedling treatment.
In clinical settings, growth factors and exosomes that have been added to cosmetic solutions have been shown to help repair and renew tissue at a high level. Following surgery, dermatologists highly recommend serums that have been specifically designed as salves. Certain types of skincare are able to distinguish themselves from over-the-counter beauty brands just by the foundational ingredients that are used. For example, the patented ingredient PTT-6® is an active ingredient that was created using stem cell wound-healing technology that is used by CALECIM® Professional. It has natural anti-aging properties, such as the ability to speed up skin repair, make skin denser, and keep skin more hydrated. In fact, in-vitro tests have measured a 600% average improvement in skin thickness, 42% more skin cell growth within seven days, and complete skin restoration in as quick as 40 hours. Patient testimonials have also attested to the more visible lifting effects, smoother facial contours, and brighter complexions, which determine that results are efficient and long-lasting.
The integration of exosomes as a microneedling post-procedure aftercare represents a significant step forward in anti-aging interventions, especially when their conception is backed by scientific evidence and clinical efficacy. With more efficient absorption rates created through the micro needling treatments, it both aids the exosomes’ role in pushing for collagen and elastin production within the skin and reduces the stressors of the treatment’s recovery process. Through the application of exosomes into the dermal layers, these aftercare serums help to speed up the skin’s renewal processes, encourage cellular repair, and bring back its health and vitality.